A man died after a collision between a 4WD and a truck on the Arnhem Highway on Friday, NT Police said.

Police director of communications Mark Wilton said in a statement that about 10:30am Friday police received a report of the 4WD and the truck colliding while travelling in opposite directions when the crash occurred.

“The driver, a 55-year-old man, was the sole occupant of the 4WD and was pronounced deceased at the scene,” Mr Wilton said.

“Major Crash Detectives are conducting a thorough investigation to determine the cause of the crash. The driver of the truck has tested negative for drugs and alcohol and is fully cooperating with the ongoing investigation.”

There have been 44 people killed on Territory roads this year, compared to nine people for the corresponding period last year.

Police are asking anyone who witnessed the incident, and have not yet spoken with them, or has dash-cam footage around the time of the crash, to call them on 131 444.