NT Police are searching for 26-year-old Isacc Thompson, who escaped custody Sunday night and went on the run in shorts, socks and handcuffs after being transferred to Royal Darwin Hospital in an ambulance, police said.

The escape occurred around 8:15pm Sunday night, while he was being escorted from an ambulance to the emergency department at RDH.

Police did not say which organisation was escorting the inmate, who they said has ties to the Mongols bikie group. He was last seen running down Rocklands Drive, but police did not say in which direction.

Police have warned the public not to approach Thompson.

“We’re asking members of the public not to approach him. If you see him, call Triple Zero immediately,” said Sgt Kenneth Bradshaw.

“Anyone who sees him or has information about his whereabouts is asked to contact police on 000 and quote reference number P26191473.”

The Fugitive Taskforce, Strike Force Trident and the Dop Operations Unit are continuing to search for the man.

The latest escape follows another Mongols member jumping the dock at Darwin Local Court last month and evading police for four days.

Tips from the public led to his recapture, while several people were charged with assisting him evade police.